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To get from Panama to Colombia, here are your other options

Fly – Planes are obviously the fastest and easiest way to get to Colombia, but not nearly as adventurous as hiking the Darien. There are non-stop flights between Panama City (PTY) and Cartagena (CTG). Find prices on Skyscanner.
Cargo ship – Cargo ships sail from Colon and/or Portobello to various Colombian port towns. Yes, you can travel by cargo ship.
Ferry – For a short time Ferry Xpress ran a car ferry between Colon and Cartagena, but service has been suspended.
Quick Speed boat – This is not for the queasy; the water can be very rough. You fly to the border town of Puerto Obaldia, then take a 3-hour boat ride to Turbo, Colombia. Buses run from Turbo to both Medellin and Cartagena (8-10 hours).
Sail from Portobello to Cartagena – This multi day journey includes a visit to the beautiful San Blas islands. Costs compare to a plane flight. Many companies offer services, such as San Blas Frontera, San Blas Adventures and Panama Travel Unlimited, and of course you can ask at your hotel/hostel or search the web. But don't automatically choose the cheapest ride. Verify the details or you might not get what you expect.
Do a hybrid journey – According to Runaway Guide, you begin your journey across the Darien Gap with a domestic flight from Panama City (PAC) to the city of Puerto Obaldia (PUE). After obtaining your exit stamp, you will then take a 30-minute motor boat to Capurgana. From here you take another boat across to Turbo, where you can then take a bus down to Medellin. Be prepared for rough seas.

napisz moze do nich maila, masz info w zakladce Charters
https://www.airpanama.com/en/charters
Puerto Obaldia jest na liscie ich destynacji